Since I don't have a pet (or live plant), I am free to travel anywhere, any time I wish, but many of my friends have pets and must plan their trips by factoring in someone to pet sit or find a place that will accommodate pets. Even Oprah has based her stays at certain hotels on whether or not they will allow her dogs to stay with her, so places which cater to pets on vacation are an invaluable service (her hotel chain of choice is the Four Seasons).
Best Friends Pet Care has boarding facilities all over the US from San Diego to Florida, with concentrations in popular family destinations, like Walt Disney World Resorts in Florida. They offer a wide range of choices from private doggy suites to cozy kitty condos. For a small daily fee they will even give one on one private play times tailored for your pet from active ball tossing to cuddling for older pets. If you live near one of their locations, you can also take advantage of their doggy day camp, grooming and training options.
If reincarnation exists I want to come back as one of Oprah's dogs, or at least as a dog who gets to stay at a place like Best Friends Day Care.